The most powerful compound in botanical medicine,
the worlds most important herbal extract.

 

What is Turmeric and Curcumin?
Turmeric is a member of the Curcuma botanical group, which is part of the ginger family of herbs, the Zingiberaceae. The root and rhizome stem of the Curcuma longa plant is crushed and powdered into ground Turmeric. Ground Turmeric is used worldwide as a seasoning and is the source of Curcumin.
curcumin turmeric

curcumin turmeric
Curcumin is a natural component of the rhizome of Turmeric (Curcuma longa) and one of the most studied phytochemicals. It is extracted, concentrated, standardized and researched in supplement form.

 

What are the researched properties of Curcumin? 

"The list of Curcumin's effects goes on and on, and they're all in your favor...in addition to its anti-inflammatory and antioxidant properties, Curcumin has several effects that may work in tandem to protect the brain from plaques in other ways. "If Curcumin had a single molecular target, it probably would not be as good a drug," M.D. Anderson Cancer Center in Houston. "But because it has multiple targets, it's very attractive." - Science News Magazine
 

"Worldwide, there are over 1000 published animal and human studies, both in vivo and in vitro in which the effects of curcumin on various diseases have been examined. Studies include epidemiological, basic and clinical research on AD." - Acad Neurol. 2008 Jan-Mar; 11(1): 13–19. The effect of curcumin (turmeric) on Alzheimer's disease: An overview
 

"A large number of studies on curcumin were identified. These included studies on the antioxidant, anti-inflammatory, antiviral, and antifungal properties" - J Altern Complement Med. 2003 Feb;9(1):161-8. Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa)
 

"Because of the crucial role of inflammation in most chronic diseases, the potential of Curcumin has been examined in neoplastic, neurological, cardiovascular, pulmonary and metabolic diseases. The pharmacodynamics and pharmacokinetics of Curcumin have been examined in animals and in humans." - Trends Pharmacol Sci. 2009 Feb;30(2):85-94. Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets.
 

"Six hundred and eighty-eight studies, more than 400 of them published within the last four years, confirm Curcumin's remarkable anticarcinogenic, anti-inflammatory, and antioxidant properties. Within the last year, interest in Curcumin's potential as a neuroprotective agent have been rising." - Worlds Healthiest Foods

 
Where can I purchase Curcumin?
Order direct from Turmeric-Curcumin.com, the largest supplier of Curcumin supplements at wholesale prices to the general public, research institutions, physicians, and university medical centers for over twelve years. Quality control tests, laboratory analysis certification, and rigorous cGMP manufacturing standards all ensure freshness, potency, and purity of content material. Orders are shipped FedEx or USPS Priority for fast and secure delivery. Contact support@turmeric-curcumin.com for bulk ordering, private labeling or any other questions. Multiple bottle orders will receive quantity discounts listed below, 12-bottle case purchases will also receive free US shipping.

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Curcumin 95% standardized herb extract.
Health-conscious consumers should be careful in selecting a Curcumin extract product, making sure that they know what they’re getting. Some buyers may have heard about Curcumin but may not be familiar with the difference between it and Turmeric, and may confuse the two. Our extract is standardized to contain a minimum of 95% Curcuminoids: Curcumin (C), Demethoxycurcumin (DMC), Bisdemethoxycurcumin (BDMC) - the complete range in their natural composition ratio of 76:19:5. Thus, in our product the full spectrum of Curcumin antioxidant Curcuminoids are extracted from Turmeric (Curcuma longa root) and represented in their natural arrangement for maximum potency. This is the same material used in clinical trials and medical studies, free of added chemicals, 'enhancements', or treatments. Unlike many antioxidants, Curcumin is capable of both preventing free radical formation, as well as neutralizing existing free radicals, and is considered an effective bioprotectant due to this dual activity. We supply the purest Curcumin available, standardized to 95% extract
 

500 milligrams per capsule.

Consumers may also be deceived by labels, believing there is much more true Curcumin in a product than there really is due to confusingly labeled products. Some examples of these misleading claims which make it difficult to tell how much active Curcumin extract is actually included are "1000 mg per serving" but the serving size is 4 capsules; 500 mg "enhanced formula" but contains only 200 mg Curcumin extract and the rest is 300 mg Turmeric; 1000 mg "super complex" which contains only 250 grams of Curcumin extract and the rest is 750 grams of Turmeric powder. The amount of "Curcumin complex" is listed on the label rather than the amount of active Curcumin extract. Thus, a product labeled "1000 mg Curcumin (25%)" does not even deliver 300 mg of Curcumin, since Turmeric powder averages only 3.14% Curcumin by weight. - 55(2):126-31. These deceptions are not uncommon in the supplement industry, even by the largest vitamin shops. The solution is to compare; look for a label that clearly indicates the contents (Curcumin extracted from Turmeric root), the concentration (95%) and the amount (500mg) for each capsule, not per serving. Our product contains 500 milligrams per capsule of 95% standardized Curcumin extract. There is no claimed "enhancing" material to fill the capsule up and lower the Curcumin percentage. Our product contains no sugars or other sweeteners, no artificial colors or flavors, no starch, no sodium, no soy, no yeast, no wheat, no gluten, no dairy, no preservatives, no black pepper extract or "bioperine" (actually a trademark of Piper nigrum by the Sabinsa corporation), no GMO, no dyes, no gums or any other unnecessary compounds.
 

200 capsules per bottle.

For the environment as well as your finances, we don't require purchasing two or three bottles to obtain 200 capsules. Each bottle contains the full 200 capsules, with every 12-bottle case totaling over two and a half pounds of pure Curcumin extract. The suggested serving size is one (1) to four (4) capsules with meals, preferably with beneficial oils and fats, potentially offsetting the inflammatory response process that occurs during ingestion and digestion.
 

Are there any side effects or interactions related to Curcumin or Turmeric?

"Curcumin is not toxic to humans up to 8,000 mg/day."- Phase I Clinical Trial of Curcumin, 21(4B):2895-900.  "Patients received 8 g curcumin by mouth daily...No toxicities were observed." -  Phase II ClinicalTrial of Curcumin, Clin Cancer Res. 14(14):4491-9. "Curcumin, even in large quantities, does not produce any known side effects in humans." - Blood.101(3):1053-62. Turmeric has been used in large quantities as a condiment for thousands of years with no adverse reactions.  The US FDA classifies Turmeric as GRAS (Generally Recognized As Safe). Pregnant women, individuals with gallstones or using blood thinners should consult a health care provider before using herbs or dietary supplements in amounts greater than usually found in foods.
 

Has the absorption and bioavailability of Curcumin 95% powder been studied?

"The average peak serum concentrations after taking 4,000 mg, 6,000 mg and 8,000 mg of curcumin were 0.51 microM, 0.63 microM and 1.77 microM, respectively." - Phase I Clinical Trial of Curcumin, 21(4B):2895-900.
 
What are the chemical properties of Curcumin?
Chemical Name Diferuloylmethane
Definition A β-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups
Systemic Name (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione)
Molecular Formula C21H20O
Molar mass 368.38 g/mol
Appearance Bright yellow-orange powder
Melting Point 183 °C, 361 °F
PubChem 969516
Biofunction Enzyme cofactor
Chemical Taxonomy Organic Chemicals / Hydrocarbons / Aromatic Compounds /  Phenols / Catechols / Curcuminoids
Chemical Structure 3D
Chemical Structure

   

Organic Source Taxonomy Kingdom
Subkingdom
Superdivision
Division
Class
Subclass
Order
Family
Genus
Species
Plantae (Plants) 
Tracheobionta (Vascular plants)
Spermatophyta  (Seed plants) 
Magnoliophyta  (Flowering plants)
Liliopsida  (Monocotyledons) 
Zingiberidae
Zingiberales
Zingiberaceae  (Ginger family) 
Curcuma (Curcuma)
Curcuma longa  (Turmeric)
 

Why Turmeric root and its extract Curcumin may provide health benefits?

Certain plants manufacture chemicals that repel predators, parasites and diseases. Like most of these pharmacologically-active metabolites, Curcumin is involved in self-defense. Over time, plants with higher levels of organic compounds that deter attackers become more successful, because of their advanced protection. In nature's never-ending interaction between predator and prey, insects evolve the ability to digest plant toxins, while plants evolve stronger chemicals to deter their enemies. Monitoring this evolution between plants and insects represents an important field of ecological research. Scientists have discovered that many phytochemicals manufactured in plants and roots not only prevent insect attack or fight plant infections, but also provide human health benefits. Many cultures create their own botanical pharmacies as the lore of medicinal plants and remedies is handed down through generations of healers. With the advent of sophisticated laboratory testing, biologists are finding that the many indigenous plants and roots from around the world provide medicinal value, and their metabolites are candidates for research. Curcumin’s structure is similar to other natural polyphenolics (chemicals containing multiple "phenol" groups) produced by plants in response to infectious attack. These natural polyphenols often have potent anti-oxidant and anti-inflammatory properties as well as immune support health benefits. Curcumin from Turmeric, resveratrol from grapes, pterostilbene from blueberries, and catechins from green tea all contain polyphenolic antioxidants and have been studied for medicinal or preventive value. Curcumin has been studied for anti-oxidant, anti-inflammatory, antiviral, antibacterial, antifungal, and anticancer activities, mediated through the regulation of various transcription factors, growth factors, inflammatory cytokines, protein kinases, and other enzymes. Curcumin exhibits activities similar to recently discovered TNF blockers (humira, remicade and enbrel), vascular endothelial cell growth factor blocker (avastin), human epidermal growth factor receptor blockers (erbitux, erlotinib, and geftinib), and HER2 blocker (herceptin). Considering the recent scientific bandwagon that multi-targeted therapy is better than mono-targeted therapy for most diseases, Curcumin is a phytonutrient that can be considered an ideal "Spice for Life". More than 5000 papers published within the past two decades have revealed that Curcumin has extraordinary potential in promoting health through modulation of numerous molecular targets.

 

What is the history of Curcumin and Turmeric?

Turmeric is an ancient spice and a traditional remedy. Its health benefits have been described for thousands of years in traditional Indian (Ayruvedic) and Chinese medicine largely because of its proven efficacy in treating conditions with inflammation. These ancient civilizations have vast trial and error experience with many different herbal remedies and food preparations and they selected curcumin as a food additive and major tool for medicinal use based on efficacy. Since 1900 BC numerous therapeutic activities have been assigned to Turmeric for a wide variety of diseases and conditions, including those of the skin, pulmonary, and gastro-intestinal systems, aches, pains, wounds  and disorders. Marco Polo, writing of his travels in China, described Turmeric in the 13th century: "There is also a vegetable which has all the properties of the true saffron, as well as the color, and yet it is not really saffron. Turmeric is held in great estimation, and being an ingredient in all their dishes, it bears, on that account, a high price."  The high degree of reverence for Turmeric is established by the fact that it is used in many cultures, each having its own name for the spice: Burmese:fa nwin.  Chinese:wong geung fun, yü chiu.  Danish:gurkemeje.  Dutch:geelwortel.  Finnish:keltajuuri.   French: curcuma, saffron des Indes.  German:gelbwurz, kurkuma.   Icelandic:turmerik.  Italian: curcuma tumeric  Indian:haldee, haridra, haldi, huldee, huldie. Indonesian:kunjit, kunyit.   Japanese:ukon circumin   Malay:kunjit.  Norwegian:gurkemeie,  Polish:klacze kurkumyPortuguese:açafrão-da-Índia.   Russian:zholty imbir.  Spanish:azafrán de la India, azafran arabe.   Sinhalese:kaha. Swedish:gurkmeja.  Tamil:munjal.   Thai:ka min.  Vietnamese:bot nghe
 
Why hasn't the pharmaceutical industry patented Curcumin?
Multinational pharmaceutical corporations tried registering patents for Curcumin and Turmeric because of the much heralded scientific evidence and the long history of its healing properties. However, that same evidence and history of Turmeric and Curcumin being used medicinally for centuries was the reason the United States Patent and Trademark Office rejected and revoked the rights for Turmeric patent 5401504 on the grounds that the claims were not new: "USPTO unequivocally rejected all six claims made on August 13, 2001 ruling that Turmeric's medicinal properties were not patentable."  University of Texas MD Anderson Cancer Center states "in the case of Curcumin, a natural compound, no company can reap the benefits if Turmeric shows itself to be an effective anti-cancer drug." This loss to Big Pharma is a gain for educated consumers.
 

What are the studied pharmacological actions of Curcumin?

Anti-inflammatory, Anticancer (Anticarcinogenic), Prostate Cancer, Breast Cancer, Ovarian Cancer, Colon cancer, Rectal cancer, Skin cancer, Melanoma, Antiphlogistic, Anti-Diabetes, Antiproliferative, Antianglogenic, Antimetastatic, Antitumoral, Antihypertensive, High-Blood Pressure, Antihepatotoxic Action Antimutagenic Action, Anti-Excessive Fluid (Antiedemic), Antihyperlipemic, Hypolipidemic, Antithrombotic Activity, Anti Psoriasis, Protects Against Kidney Injury, Anticoagulant - Prevents blood clotting, Prevention of Memory Loss, Chemoprotective, Neutralizing of Free Radicals, Inflammatory Bowel Disease ,Ulcerative Colitis Protection Diabetic Retinopathy, Antiangiogenic, Increases HDL (Good) Cholesterol levels, Cholagogue, Lowers LDL (bad) cholesterol levels, Choleretic Hepatoprotective, Antimicrobial, Anti-tumor, Suppresses Tumor Growth, Antiviral, Antiparasitic, Anti Cystic Fibrosis, Chronic Fatigue Syndrome, Depurative - Promotes excretion and removal of waste material, Anti-HIV - Inhibits Interleukin-1, Proapoptotic, Anti-amyloidogenic prevention of Alzheimer's disease, Antihypercholesterolemic, Helps prevent oxidation of blood cholesterol, Helps protect against or lessen the degree of kidney lesions, Antioxidant, protects against free radical damage, Angiogenesis, the generation of new blood vessels, Prevention of degenerative bone loss (Osteoporosis), Prevention of joint stiffness (Arthritis), Carminative, Increases digestive fluids and reduces gas, Cardiovascular protection and heart disease prevention
   
How may Curcumin work against cancer?
Independent research studies on suggest that Curcumin has the potential for treatment of cancers including colon, breast, prostate, lung, skin and bowel. Curcumin is one of the most powerful and promising chemopreventive and anticancer agents, and epidemiological evidence demonstrates that people who incorporate high doses of this spice in their diets have a lower incidence of cancer. Curcumin's epigenetic modulation has been studied by the US National Cancer Institute (NCI) and academic investigators around the world. Because of low toxicity and great efficacy in multiple in vitro and in vivo cancer models, Curcumin was selected for further development, put through extensive toxicology testing and has successively made it through the first stages (Phase I) of clinical testing abroad and is currently in clinical trials at several sites in the U.S. Numerous mechanisms have been described for the anticancer activity of Curcumin. Researchers at M.D. Anderson Cancer Center in Houston, TX state that Curcumin has “enormous” potential to prevent and treat cancer. Curcumin was able to suppress tumor formation, growth, and even metastasis according to their review. Currently, there are clinical trials being conducted on the effects of Curcumin on patients with bowel cancer.  Inhibition of proliferation of tumor cells, induction of apoptosis (a mode of cell death), inhibition of transformation of cells from normal to tumor, inhibition of invasion and metastasis and suppression of inflammation have been linked with the activity of Curcumin. Down-regulation of COX2, 5-LOX, adhesion molecules, inflammatory cytokines, chemokines, growth factor receptors, vascular endothelial growth factor (VEGF) and transcription factors by Curcumin have been linked to its antitumor activity. Curcumin also has been studied with regards to the core inflammatory gene signal, NF-kappaB, resulting in a beneficial domino effect throughout the body. One benefit of this domino effect is a direct reduction in the risk of cancer from overweight-induced inflammation.
 
How may Curcumin work against arthritis?
Arthritis is also a proinflammatory disease. All current drugs approved for arthritis have anti-inflammatory activity. Anti-TNF (tumor necrosis factor) therapy has been approved for this disease. Curcumin has been shown to both suppress the TNF production, block the action of TNF, and have activity against arthritis. When inflammation is reduced, the added benefit is pain relief. A double-blind, crossover study showed that Curcumin may be  effective in relieving pain and improvements in morning stiffness, walking time, and joint swelling.
 
How may Curcumin work against Crohn's disease and Ulcerative Colitis?
Crohn’s disease is also a pro-inflammatory disease. All current drugs approved for this disease have anti-inflammatory activity. Anti-TNF therapy has been approved for this disease. Curcumin has been shown to both suppress the TNF production and the TNF action. Curcumin taken orally has been shown to have activity against inflammatory bowel disease. Study results suggest that Curcumin could have a protective role in ulcerative colitis via regulation of oxidant/anti-oxidant balance and modulation of the release of some inflammatory endocoids, namely TNF-alpha and NO. The development of DSS-induced colitis was significantly attenuated by curcumin. Inhibition of p38 MAPK signaling by curcumin could explain the reduced COX-2 and iNOS immunosignals and the nitrite production in colonic mucosa, reducing the development of chronic experimental colitis. In addition, Curcumin seems promising with regards to remission in patients with quiescent Ulcerative Colitis.
 
How may Curcumin work against against diabetes?
Curcumin acts directly on liver cells to help prevent them from becoming fatty, and studies have concluded that Curcumin may have an anti-diabetic effect by decreasing serum fatty acid through the promotion of fatty acid oxidation and utilization. Curcumin also works directly on pancreatic beta cells to help them produce insulin normally. By helping the liver and the pancreas, Curcumin is taking stress off the two most important organs whose function declines before the onset of type 2 diabetes. Curcumin also influences key hormones, supports major body organs, and regulates inflammatory signaling all in ways that help correct or prevent metabolic problems. Curcumin helps lower inappropriately high levels of leptin (reducing leptin resistance) while boosting the all-important levels of the adiponectin (which lowers insulin resistance). Curcumin also helps activate the fat-burning gene signal PPAR gamma, which also helps to make more new, metabolically-fit fat cells. Curcumin directly reduces major inflammatory events from occurring inside white adipose tissue (tumor necrosis factor alpha, interleukin-6, and monocyte chemotactic protein-1). By lowering such inflammation, the source of overweight-induced disease is targeted.
 
How may Curcumin work against obesity and overweight-induced metabolic syndrome?
In the prevention and treatment of obesity and metabolic syndrome, Curcumin has been reported to modulate numerous targets that have been linked to obesity and insulin resistance. First, Curcumin has been shown to downregulate the expression of TNF in various tissues. Second, our laboratory was the first to demonstrate that Curcumin can suppress NF-κB activation induced by a wide variety of inflammatory agents through inhibition of degradation of IκBα. Third, Curcumin can inhibit the activation of IKK linked to the activation of NF-κB, and this leads to the suppression of expression of inflammatory biomarkers such as cyclooxygenase-2 (COX-2) and vascular endothelial growth factor. Fourth, the spice has been shown to downregulate the expression of various NF-κB-regulated proinflammatory adipocytokines including chemokines (such as MCP-1, MCP-4, and eotaxin) (199) and interleukins (IL-1, IL-6, and IL-8). Curcumin also suppressed the expression of plasminogen activator inhibitor type-1 through the inhibition of the transcription factor early growth response (Egr)-1 gene product that has been closely linked with insulin resistance and obesity. Fifth, it has been reported to mimic most antidiabetic drugs in that it activates PPAR-γ in hepatic stellate cells. Sixth, this nutraceutical has been shown to downregulate activation of c-Jun NH2 terminal kinase. Seventh, Curcumin has been shown to inhibit the Wnt/β-catenin pathway, which is closely linked to obesity. Later studies have indicated that Curcumin inhibits Wnt pathway signaling through downregulation of the transcription coactivator p300. Another potential mechanism by which Curcumin could inhibit β-catenin signaling is through inhibition of glycogen synthase kinase (GSK)-3β, which directly causes the phosphorylation of β-catenin. Curcumin was found to inhibit GSK-3β with as little as 66 nM IC50 (32). Eighth, the spice has been shown to induce the expression of hemeoxygenase (HO)-1 through the activation of Nrf2 in pancreatic cells and thus mediate the survival of these cells. Ninth, curcumin downregulates the secretion of insulin-like growth factor-1 but induces the expression of insulin-like growth factor binding protein-3. Tenth, this nutraceutical interrupts leptin signaling by reducing phosphorylation levels of the leptin receptor (Ob-R) and its downstream targets. In addition, curcumin suppresses gene expression of Ob-R in HSCs. Finally, curcumin has been reported to increase the expression of adiponectin, which negatively controls obesity.
 
How may Curcumin work against psoriasis?
Psoriasis is another pro-inflammatory disease. Considerable evidence, both in animals and humans, indicates that Curcumin may be effective against psoriasis.
 
How may Curcumin work against Alzheimer's disease?
Researchers found that Curcumin not only reduces oxidative damage and inflammation, but also reduces amyloid accumulation and synaptic marker loss and promotes amyloid phagocytosis and clearance. Curcumin worked to prevent synaptic marker and cognitive deficits caused by amyloid peptide infusion and abeta oligomer toxicity in vitro, and may help the immune system clear the brain of amyloid beta, which forms the plaques found in Alzheimer's disease. Clinical trials are in progress at UCLA with Curcumin for Alzheimer's. In the Alzheimer’s Disease Anti-Inflammatory Prevention Trial, researched showed that reducing inflammation has positive effects on patients with Alzheimer’s. Curcumin significantly lowered several inflammation markers, in addition to reducing plaque on the brain (a sign of Alzheimer’s) by 43 to 50 percent.
 
How may Curcumin work as an Anti-inflammatory?
Turmeric is safe and non-toxic and has been studied for anti-inflammatory properties, inhibiting various molecules that contribute to inflammation such as lipooxygenase, COX-2, leukotrienes, prostaglandins, nitric oxide, interferon-inducible protein, tumor necrosis factor (TNF), and interleukin-12 (IL-12).  One study compared the effectiveness of Curcumin – the active ingredient in turmeric – and a popular non-steroidal anti-inflammatory drug (NSAID) called phenylbutazone. At the end of the six days, those taking the Curcumin and the NSAID enjoyed a significantly better anti-inflammatory response than placebo. The spice worked as well as the drug, but without the negative side effects.
 
Recent news and published studies on Curcumin and Turmeric

May 2013

Curcumin prevents obesity, diabetes and fatty liver

Food Consumer 2013 May
Curcumin an ingredient found in turmeric has been used to prevent many chronic diseases including obesity, type type 2 diabetes and liver disease.  Recent studies show that this dietary supplement possesses potent antioxidant, anticarcinogenic, antiinflammatory and hypoglycemic properties.

Citrus limonoids and curcumin additively inhibit human colon cancer cells.

Food Funct. 2013 Apr
This study provides compelling evidence of the pharmacodynamic additive effect of limonoids and curcumin in inhibiting human colon cancer cells. These results suggest that consumption of curcumin and limonoids together may offer greater protection against colon cancer.

Antidepressant-Like Effects of Curcumin.

CNS Neurol Disord Drug Targets. 2013 Apr
Curcumin, the major constituent of the spice turmeric produces a plethora of biological actions that have translated in vivo into behavioral and neurochemical effects in rodents that are also produced by clinically-used antidepressants.

Curcumin Attenuates Diet-Induced Hepatic Steatosis by Activating AMPK.

Basic Clin Pharmacol Toxicol. 2013 Apr
Curcumin is a well-known component of traditional turmeric (Curcuma longa), which has been reported to prevent obesity and diabetes. The levels of total cholesterol, fasting glucose and insulin in serum were decreased, and HFD-induced impairment of insulin sensitivity was improved by curcumin supplementation

Curcumin inhibits UVB

Exp Dermatol. 2013 Apr
Curcumin (diferuloylmethane) is a polyphenol derived from turmeric (Curcuma longa), which is commonly used as a spice. Recent studies have shown that curcumin has a wide range of pharmacological activities, including anticarcinogenic, antioxidant, anti-inflammatory and antiangiogenic activities.... Curcumin prevented UVB-induced MMP expression

Curcumin improves spatial memory and decreases oxidative damage in aged female rats.

Biogerontology. 2013 Apr
Curcumin is the active component of curcuma longa and has shown antioxidant, antiinflamatory and neuroprotective properties...curcumin supplementation improves cognitive functions by decreasing the lipid peroxidation in brain tissue of aged female rats.

Curcumin And Curcumin-Like Molecules: From Spice To Drugs.

Curr Med Chem. 2013 Apr
Curcumin is the major yellow pigment extracted from turmeric, a commonly used spice in Asian cuisine that is used extensively in ayurvedic herbal remedies. A number of studies have shown that curcumin can be a prevention agent and a chemotherapeutic agent for colon, skin, oral and intestinal cancers. Curcumin is also well-known for its anti-inflammatory and antioxidant properties, showing high reactivity towards peroxyl radicals, and thus acting as a free radical scavenger.

Genetic And Epigenetic Studies For Determining Molecular Targets Of Natural Product Anticancer Agents

Curr Cancer Drug Targets. 2013 Apr
Accumulating evidence has demonstrated that some common natural products (such as epigallocatechin-3-gallate (EGCG), curcumin, genistein, sulforaphane (SFN) and resveratrol) have anticancer properties through the mechanisms of altering epigenetic processes and targeting cancer stem cells (CSCs). These bioactive compounds are able to revert epigenetic alterations in a variety of cancers in vitro and in vivo. They exert the anticancer effects by targeting various signaling pathways related to the initiation, progression and metastasis of cancer. It appears that natural products hold great promise for cancer prevention and treatment by altering various epigenetic modifications.

Attenuation of age-related increase of protein carbonylation in the liver of mice by melatonin and curcumin

Mol Cell Biochem. 2013 Apr
Curcumin, a phytochemical, has a wide variety of biological actions including anti-inflammatory and antioxidative....the formation of protein carbonyls in the liver of the aging mice can be prevented by the antioxidative effects of melatonin and curcumin, which may provide health benefits in aging animals.

Curcumin inhibits invasion and metastasis in K1 papillary thyroid cancer cells.

Food Chem. 2013 Apr
Curcumin, the active constituent of dietary spice turmeric, possesses a strong potential for cancer prevention and treatment...The findings showed that curcumin might be an effective tumouristatic agent for the treatment of aggressive papillary thyroid carcinomas.

Neuroprotection by curcumin in ischemic brain injury

PLoS One. 2013 Apr
Curcumin administration significantly reduced infarct size. Curcumin also markedly reduced oxidative stress levels in middle cerebral artery occlusion (MCAO) rats; Taken together, these findings provide evidence that curcumin protects neurons against ischemic injury, and this neuroprotective effect involves the Akt/Nrf2 pathway. In addition, Nrf2 is involved in the neuroprotective effects of curcumin against oxidative damage.

Anti-Obesity Agents Have the Potential to Inhibit Fat Gain Right at the Cellular Level

Suppversity 2013 Apr
The stimulatory effect curcumin exerts on the AMPK expression of adipocytes results in a down-regulation of PPAR-gamma in 3T3-L1 adipocytes

Supplement Your Health With Curcumin

Wayne County Journal Banner 2013 Apr
Curcumin may have the power to ease inflammation, promote healthy cell growth, protect against ... The main bioactive compound in turmeric is called curcumin.

Curcumin is a complete well-being tonic – it benefits every organ in the body… It shows promise of fighting nearly every disease

Marks Daily Apple 2013 Apr
Curcumin Controls Blood Sugar: It switches on the liver genes that keep glucose levels in check. It improves the pancreas’s ability to make insulin and helps slow down the metabolism of carbohydrates after meals. Curcumin Fights Cancer: It inhibits the genetic switches that allow for cancerous cell growth to occur. Curcumin Speeds Up Metabolism: USDA research shows that is enhances cellular energy to speed metabolism. Curcumin Clears Plaque: It removes amyloyd plaque buildup in the brain that can cause Alzheimer’s.

Curcumin inhibits inflammatory response and bone loss during experimental periodontitis in rats.

2013 Mar
Curcumin, an active ingredient of turmeric, is proved to be a potential candidate of controlling inflammation and bone resorption (and) may decrease alveolar bone loss in the experimental periodontitis rats via suppressing the expression of RANKL/RANK/OPG and its anti-inflammatory properties.

Hibiscus sabdariffa linnaeus (malvaceae), curcumin and resveratrol as alternative medicinal agents against metabolic syndrome.

2013 Mar
Curcumins, derived from the spice turmeric, and resveratrol, polyphenols found in grapes and red wine respectively, in addition to their antioxidant and anti-inflammatory properties, inhibit preadipocyte proliferation, de novo lipogenesis and fat accumulation in liver....The therapeutic use of curcumin and resveratrol, in the context of obesity as an initiator of insulin resistance and hypertension, the two main features of MS, together with the underlying mechanisms of action.

Curcuminoids distinctly exhibit antioxidant activities and regulate expression of scavenger receptors and heme oxygenase-1

Mol Nutr Food Res. 2013 Mar
Curcumin (CUR), demethoxycurcumin (DMC), and bisdemethoxycurcumin (BDMC) have been demonstrated as having antioxidant, anticarcinogenic, and hypocholesterolemic activities. We report the diverse antiatherogenic effects and mechanisms of curcuminoids. Curcumin was the most potent antioxidant.

Curcumin improves expression of SCF/c-kit through attenuating oxidative stress and NF-kappaB activation in gastric tissues of diabetic gastroparesis rats.

2013 Mar
Curcumin is known to have antioxidant and anti-inflammatory properties. Curcumin treatment improved gastric emptying by blocking the production of oxidative stress, abolishing NF-kappaB signal transduction and enhancing expression of SCF/c-kit in rats with diabetic gastroparesis.

Mitochondrial dysfunction mediated cisplatin induced toxicity: Modulatory role of curcumin.

2013 Mar
Curcumin is a known cytoprotectant with comprehensive anti-inflammatory and anti-cancerous properties...Curcumin should be investigated as a potential safe and remarkable approach in attenuating the adverse effects induced by CP-related toxicants.

Curcumin Ameliorates the Neurodegenerative Pathology in A53T α-synuclein Cell Model of Parkinson's Disease

2013 Mar
Curcumin
could be a candidate neuroprotective agent by inducing macroautophagy, and needs to be further investigated by clinical application in patients suffering Parkinson's disease.

Curcumin improves expression of SCF/c-kit

Curcumin is known to have antioxidant and anti-inflammatory properties. Curcumin treatment improved gastric emptying by blocking the production of oxidative stress, abolishing NF-kappaB signal transduction and enhancing expression of SCF/c-kit in rats with diabetic gastroparesis.

Synergistic anticancer effects of curcumin and resveratrol in Hepa1-6 hepatocellular carcinoma cells.

Oncol Rep. 2013 Feb
Curcumin and resveratrol are the major anticancer constituents of Curcuma aromatica and Polygonum cuspidatum, respectively. Curcumin and resveratrol have been found to exhibit a synergistic anticancer effect in colon cancer...Curcumin and resveratrol is a promising novel anticancer strategy for liver cancer. The present study also provides new insights into the effective mechanism of paired-herbs in traditional Chinese medicine.

Curcumin prevents liver fat accumulation and serum fetuin-A increase in rats fed a high-fat diet

J Physiol Biochem. 2013 Feb
Curcumin is extracted from the rhizome Curcuma longa and has been shown to possess potent antioxidant, anticarcinogenic, anti-inflammatory, and hypoglycemic properties...Curcumin treatment appeared to be effective in reducing liver triglycerides and serum fetuin-A levels. These findings suggest that the reduction of fetuin-A may contribute to the beneficial effects of curcumin in the pathogenesis of obesity.

Integrating Dietary Supplements Into Cancer Care

Integr Cancer Ther. 2013 Feb
A list of leading supplements that have the best suggestions of benefit was constructed by leading researchers and clinicians who have experience in using these supplements. This list includes curcumin...

Curcumin: An Orally Bioavailable Blocker of TNF and Other Pro-inflammatory Biomarkers

Br J Pharmacol. 2013 Feb
Curcumin (diferuloylmethane), a component of turmeric (Curcuma longa) that is very inexpensive, orally bioavailable, and highly safe in humans, yet can block TNF-α action and production in in vitro models, in animal models, and in humans. In addition, we provide evidence for curcumin's activities against all of the diseases for which TNF blockers are being used.

Curcumin prevents mitochondrial dysfunction in the brain of the senescence-accelerated mouse

Neurochem Int. 2013 Feb
Curcumin emerges as a promising nutraceutical for the prevention of neurodegenerative diseases that are accompanied or caused by mitochondrial dysfunction.
 

  • Curcumin Enhances the Effect of Chemotherapy against Colorectal Cancer Cells

    Institute of Anatomy, Munich, Germany. 2013 Feb
    Combining Curcumin with conventional chemotherapeutic agents such as 5-FU could provide more effective treatment strategies against chemoresistant colon cancer cells

    Antidepressant-like effects of curcumin in WKY rat model of depression is associated with an increase in hippocampal BDNF.

    Behav Brain Res. 2013 Feb
    Department of Pharmacology, Howard University College of Medicine

    Curcumin is the principal active ingredient found in turmeric (Curcuma longa), a plant used in traditional Asian diets and herbal medicines. It is known to have a wide range of biological actions including antidepressant-like effects which have been observed in stress-induced depression models...Evidence for an antidepressant-like effect of curcumin, possibly through increased neurotrophic activity, in the WKY model of depression, and support the notion that curcumin may prove an effective and lasting natural antidepressant.

    Curcumin induces apoptotic cell death of activated human CD4+ T cells via increasing endoplasmic reticulum stress and mitochondrial dysfunction.

    Int Immunopharmacol. 2013 Feb
    Curcumin, a natural polyphenolic antioxidant compound, exerts well-known anti-inflammatory and immunomodulatory effects, the latter which can influence the activation of immune cells including T cells. Furthermore, curcumin can inhibit the expression of pro-inflammatory cytokines and chemokines, through suppression of the NF-κB signaling pathway. The beneficial effects of curcumin in diseases such as arthritis, allergy, asthma, atherosclerosis, diabetes and cancer may be due to its immunomodulatory properties.

    Neurobiological and pharmacological validity of curcumin in ameliorating memory performance of senescence-accelerated mice

    Pharmacol Biochem Behav. 2013 Feb
    Curcumin, a major active component of spic turmeric, could increase the capacity of learning and memory in the aged rat...Curcumin treatment could attenuate cognitive deficits of SAMP8 mice in a dose-dependent manner by decreasing the oxidative stress and improving the expression of p-CaMKII and p-NMDAR1 in the hippocampus. Thus treatment with curcumin may have a potential therapeutic agent for aging-related cognitive dysfunctions.

    Curcumin Inhibits UV Radiation-Induced Skin Cancer in SKH-1 Mice.

    Otolaryngol Head Neck Surg. 2013 Feb
    Curcumin, a naturally occurring food substance and anticarcinogenic agent, inhibited cutaneous squamous cell carcinoma xenograft growth...Curcumin appears to inhibit skin cancer formation and prolong time to tumor onset when administered by either an oral or topical route.

    Curcumin ameliorates arterial dysfunction and oxidative stress with aging.

    Exp Gerontol. 2013 Feb
    Curcumin supplementation ameliorates age-associated large elastic artery stiffening, vascular endothelial dysfunction, oxidative stress and increases in collagen and AGEs in mice...Curcumin may be a novel therapy for treating arterial aging in humans.

    Curcumin restores diabetes-induced neurochemical changes in the brainstem of Wistarrats.

    Eur J Pharmacol. 2013 Feb
    B
    eneficial effect of curcumin in diabetic rats by regulating the cholinergic, insulin receptor and GLUT-3 in the brainstem similar to the responses obtained with insulin therapy.

    A potent neuroprotective modulator against Alzheimer disease.

    Fundam Clin Pharmacol. 2013 Feb
    Some substances, such as Zn, s-Ethyl cysteine, s-propyl cysteine, citicoline, rivastigmine, Vit E, memantine, tea polyphenol, curcumin, caffeine, Alpinia galanga (L.) fractions, and Bacopa monnieri could play a role in improving memory performance and exert protective effects against
    Alzheimer disease.

    Complementary therapies in cystic fibrosis: nutritional supplements and herbal products.

    J Pharm Pract. 2013 Feb
    Complementary therapies in cystic fibrosis such as vitamin A, vitamin C, vitamin E, zinc, omega 3 fatty acids, docosahexaenoic acid (DHA), garlic, ginseng, and curcumin.

    The molecular mechanism of action of aspirin, curcumin and sulforaphane combinations in the chemoprevention of pancreatic cancer.

    Mar, 2013
    Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences
    Chemopreventive potential of a combination of aspirin (ASP), curcumin (CUR) and sulforaphane (SFN) in low doses to human pancreatic cancer cells

    Curcumin induces FasL-related apoptosis through p38 activation in human hepatocellular carcinoma Huh7 cells.

    2013 Mar
    Underlying molecular mechanism of curcumin-induced apoptosis in human hepatocellular carcinoma (HCC) Huh7 cells.

    Curcumin attenuates endothelial cell oxidative stress injury through Notch signaling inhibition.

    2013 Mar
    The protective effects of curcumin against OSI (oxidative stress injury)
     

    Bioactivity of turmeric-derived curcuminoids and related metabolites in breast cancer.

    Endocrinology Section, Department of Medicine, The University of Arizona-Feb 19, 2013
    The structural and biological importance of curcuminoids in the anti-breast cancer effects of turmeric and contradict recent assertions that certain of the curcuminoid metabolites studied here mediate these anti-cancer effects.

    Diet of curry may add health benefits

    mySteinbach.ca-Feb 2, 2013
    Curcumin, which provides the beautiful orange-yellow color to the turmeric root, achieves its protective quality, ...
     
  • Turmeric: sprinkle on this spice for good health

    Chiropractic Economics-Jan 11, 2013
    Curcumin, which gives turmeric its yellow color, has anti-inflammatory and ... Curcumin initiates the self-destruction of cancer cells and prevents their growth.
     
  • Spice may be new route to good health

    Palm Beach Daily News-Jan 6, 2013
    Curcumin, a phenol responsible for making turmeric yellow, does much more than provide numerous Indian dishes with that particular tint, according to Dr.
     
  • Alzheimer's and a Healthy Lifestyle

    GroundReport Jan 2, 2013
    Curcumin with its rich anti-inflammatory components. The spice is widely used in India and it's interesting to note that elderly villagers in India have one of the world's lowest rates of Alzheimer's.
     

    Turmeric Helps Conquer Arthritic Inflammation

    GreenProphet Jan 2, 2013
    This review of preclinical and clinical trials with curcumin submitted to PubMed.gov is only one of many publications attesting to its anti-inflammatory powers.

    Rheumatoid Arthritis and Curcumin, What Studies Show

    eMaxHealth-Dec 13, 2012
    If you currently take over-the-counter or prescription medications to treat pain and other symptoms of rheumatoid arthritis (RA), you may want to consider spicing ...
  • Top Five Supplements for Women

    Scoop.co.nz-Dec 10, 2012
    Curcumin Curcumin is an extract from the curry spice, turmeric (approximately 5% of turmeric is ... Through clinical trials, curcumin has demonstrated antioxidant, ...
  • Top supplements women should not go without

    Voxy-Dec 10, 2012
    Curcumin is an extract from the curry spice, turmeric (approximately 5% of turmeric is ... Through clinical trials, curcumin has demonstrated antioxidant, ...
  • Brainy Botanicals

    Natural Products INSIDER-Dec 6, 2012
    Curcumin, the principal curcuminoid of the Indian spice turmeric, is a strong antioxidant known to fight inflammation, but other research has centered on its ability ...
  • Genistein abrogates G2 arrest induced by curcumin in p53 deficient ...

    7thSpace Interactive -Dec 1, 2012
    Methods: T47D cell line was treated with different concentrations of curcumin and genistein, alone or in combination; added together or with interval time.
  • Curcumin vs. aerobic exercise: Both promote significant & equal ...

    ProHealth-Nov 13, 2012
    We investigated the effects of curcumin ingestion and aerobic exercise training on ... women were assigned to 3 groups: control, exercise, and curcumin groups.
  • Curcumin extract for prevention of type 2 diabetes.

    Diabetes Care. 2012 Nov;35(11):2121-7.
    This study demonstrated that the curcumin intervention in a prediabetic population may be beneficial.

    Effects of curcumin on stem-like cells in human esophageal ...

    7thSpace Interactive-Nov 1, 2012
    Many cancers contain cell subpopulations that display characteristics of stem cells. Because these cancer stem cells (CSCs) appear to provide resistance to ...
  • Curcumin: An ancient remedy for cancer prevention and survival

    nwitimes.com-Oct 29, 2012
    Patients undergoing cancer treatment often look to augment their health through alternative means. Many integrative medical interventions can make a real ...
  • The effects of turmeric therapy on cerebral malaria studied

    Medical Xpress-Oct 24, 2012
    Dr Saparna Pai has been awarded an Australian Academy of Science Early-Career Australia-India Fellowship to investigate curcumin's action on immune cells ...
  • Turmeric for liver damage, cancer

    The Guardian -Oct 17, 2012
    RESEARCHERS have found that the primary polyphenol in turmeric, curcumin, is able to repair and even regenerate the liver tissues in diabetic rats.
  • Curcumin Inhibits Prostate Cancer Metastases

    Food Product Design-Oct 15, 2012
    MUNICH—Curcumin, an active component of turmeric that has been found to inhibit inflammation, may help slow down prostate cancer metastases, according to ...
  • Curcumin may be useful for cancer prevention

    Examiner.com-Oct 14, 2012
    Timothy J. Moynihan, M.D. has written for Mayo Clinic that curcumin, which is a ... Some research has suggested that curcumin may help prevent or treat cancer.
  • Prostate cancer restricted by curcumin

    allvoices-Oct 13, 2012
    The poly-phenol found in turmeric called curcumin known for its powerful ... In a new study curcumin has been shown to have a new role when it comes to ...
  • Indian curry spice 'curbs metastases'

    TruthDive-Oct 12, 2012
    Curcumin is well tolerated and is therefore, in principle, suitable both for prophylactic use and also for the suppression of metastases in cases where an ...
  • Curry treatment for Alzheimer's

    HealthCanal.com-Oct 12, 2012
    Curcumin is already known to be a powerful antioxidant and an anti-inflammatory and could combat beta amyloid, a protein responsible for Alzheimer's and ...
  • Efficacy of Herb in IBD Treatment

    Gastroenterology & Endoscopy News-Oct 11, 2012
    More research is needed to determine the efficacy of curcumin in the treatment of inflammatory bowel disease (IBD), according to a systematic review of the ...
  • Low level curcumin supplements have 'diverse' health effects

    NutraIngredients.com-Oct 5, 2012
    Curcumin, the natural pigment that gives the spice turmeric its yellow colour, has increasingly come under the scientific spotlight in recent years, with studies ...
  • Scientists trial curry chemical in dementia fight

    Radio Australia-Oct 4, 2012
    Curcumin is the compound that gives turmeric its rich yellow colour. Scientists have found it is also a powerful antioxidant, an anti-inflammatory, and may halt the ...
  • Fighting cancer starts with what's on your plate

    Dominican Today-Oct 3, 2012
    Found in turmeric, curcumin displays anti-tumor and antioxidant properties. Curcumin is a popular Indian spice that is a member of the ginger family. It's quite ...
  • Curcumin, vitamin C fight fluoride-induced renal injury

    Food Consumer-Oct 2, 2012
    The study also showed that intraperitoneal administration of curcumin at a dose of ... For the study, one week after the treatments with fluoride and curcumin, the ...
  • Curcumin Cuts Alzheimer's Risk, Heart Disease

    Food Product Design-Oct 1, 2012
    COLUMBUS, Ohio—Curcumin, a compound found the popular Indian spice turmeric may help lower inflammatory markers associated with heart disease, ...
  • Turmeric can soothe gastric inflammation, ulcers

    indiatvnews.com-Sep 23, 2012
    Curcumin is its major component responsible for the spice's yellow colour and its ... "It (curcumin) has been shown to be a good cure for gastric ailments like ...
  • Integrative Medicine: Curcumin may aid diabetes fight

    Sacramento Bee-Sep 20, 2012
    Curcumin is felt to be the primary active ingredient in turmeric. At the end of the study, none of the people who was taking the curcumin capsules had developed ...
  • Curcumin Lowers Triglycerides

    Natural Products -Sep 18, 2012
    Supplementing with 1 g/d of curcumin for 30 days led to a significant reduction in serum triglycerides, in a recent study published in ...
  • Inhibition by curcumin of multiple sites of the transforming growth ...

    7thSpace Interactive-Sep 16, 2012
    Inhibition by curcumin of multiple sites of the transforming growth factor-beta1 signalling pathway ameliorates the progression of liver fibrosis induced by carbon ...

    Rosemary extract with curcumin fight ER-negative breast ...

    Food Consumer-Sep 5, 2012
    Additionally, carnosic acid exhibits synergy with turmeric/curcumin against breast cancer cells. These two compounds inhibited the activity of the purified ...
  • The secret recipe for longer life

    Stuff.co.nz-Sep 4, 2012
    The controversial bit comes with his inclusion of supplements like curcumin and ... Curcumin, the pigment that gives the spice turmeric it's yellow colour, is an ...
  • The anti-ageing recipe

    Sydney Morning Herald -Sep 4, 2012
    Supplements like Curcumin, the pigment that gives the spice turmeric it's yellow colour, is an anti-inflammatory, which – in animal studies - shows promise against both Alzheimer's and cancer....
  • Turmeric Improves Blood Glucose in Type 2 Diabetes

    eMaxHealth-Sep 1, 2012
    Curcumin, a major component of turmeric, is usually the ingredient people most associated with providing health benefits. In fact, curcumin has been the subject ...
  • Turmeric stopped deadly Rift Valley Fever

    UPI.com-Aug 24, 2012
    25 (UPI) -- Curcumin, found in turmeric, stopped the potentially deadly Rift Valley ... However, in the published article, we provide evidence that curcumin may ...
  • The healing spice: curcumin

    Emory Health Now -Aug 24, 2012
    A recent article in Chemical & Engineering News describes the promising properties of curcumin, a compound derived from turmeric, in models of Alzheimer's ...
  • Spicy solution for viral infection

    News-Medical.net-Aug 22, 2012
    Curcumin, the main compound in the spice turmeric, prevents replication of ... However, "we provide evidence that curcumin may interfere with how the virus ...
  • Curcumin Stops Rift Valley Fever Virus

    eMaxHealth-Aug 20, 2012
    The popular spice curcumin has been shown to stop the Rift Valley fever virus dead in its tracks, which may not seem highly relevant to people who don't live in ...
  • Curcumin could ultimately support drug therapies to defeat ...

    ProHealth-Aug 17, 2012
    Curcumin, a bioactive component of the popular spice turmeric, “shows ... that curcumin can stop multiplication of the potentially deadly Rift Valley Fever virus in ...
  • Curcumin found in Turmeric Spice prevented spread of Virus

    Best Syndication-Aug 16, 2012
    (Best Syndication News) - Researchers from George Mason University found that turmeric's curcumin was able to stop the deadly Rift Valley Fever virus from ...
  • Turmeric Spices Up Virus Study

    ScienceBlog.com -Aug 16, 2012
    Curcumin, found in turmeric, stopped the potentially deadly Rift Valley Fever virus from multiplying in infected cells, says Aarthi Narayanan, lead investigator on ...
  • Turmeric May Have the Key to Alzheimer's Disease

    India West-Aug 16, 2012
    Curcumin (the bioactive component of turmeric, used in day-to-day cooking and ... Studies on mice seemed to show that curcumin actually reversed a cause of ...
  • Curry Compound May Lower Diabetes Risk

    WebMD - August 2, 2012
    Small Study Suggests Curcumin May Play a Role in Diabetes Prevention ... July 31, 2012 -- Curcumin, the substance found in the spice turmeric that gives curry ...
  • Curry spice helps pre-diabetes

    Healthcare Today - August 2, 2012
    Curcumin, a compound in the spice turmeric, may help prevent diabetes in people who have pre-diabetes, according to the research, which was published in the ...
  • Curcumin And Factors That May Lower Diabetes ...

    Huffington Post - August 1, 2012
    A curry compound could help to keep diabetes at bay among people most at risk, a small new study shows. The research, published in the journal Diabetes ...
  • Curcumin, curry ingredient, helps cut diabetes risk, says study

    GlobalPost - August 1, 2012
    Curcumin, a component of curry, was found to cut the risk of type 2 diabetes in a new study. Researchers at the University of Nakomnayok in Thailand found that ...
  • Curry linked to lower risk of type 2 diabetes

    Examiner.com - July 31, 2012
    Curcumin, the spice known for giving curry dishes their very distinct flavor and color was placed under the microscope and unveiled some exciting results.
  • Curry Spice Can Help Decrease Diabetes Risk, New Study Reveals

    Foodbeat - July 13 2012
    The individuals were randomly assigned to take wither curcumin capsules or a ... The daily dosage for those taking curcumin capsules was 250 milligrams of ...
  • Curcumin May Prevent Diabetes in Prediabetes Patient

    Diets In Review - July 12 2012
    Curcumin is a compound in turmeric, a spice in the ginger family that's most commonly found in Indian cooking. According to an article in Reuters, previous lab ...
  • Curcumin Could Preserve Walking Ability Among Spinal Cord Injury ...

    Huffington Post - July 3, 2012
    A curry spice may do more than just add some flavor to your dishes -- it could also help to preserve the ability to walk in people who've had a ...
  • What is Curcumin?

    The International News Magazine - July 1, 2012
    USA 30 June 2012. What is Curcumin and why is this herb so popular? Why are the world and the medical community going gaga behind this ...

    Diet enriched with curcumin and DHA can promote neuroprotection in chronic SCI

    News-Medical.net - ‎Jun 27, 2012‎
    Researchers from the Department of Neurosurgery at the David Geffen School of Medicine and the Department of Integrative Biology and Physiology at UCLA have found that a diet enriched with docosahexaenoic acid (DHA), an omega-3 fatty acid, and curcumin ...

    DHA and curcumin help maintain neurological function after degenerative damage

    News-Medical.net - ‎Jun 27, 2012‎
    The second group consumed a standard diet supplemented with docosahexaenoic acid, or DHA, and curcumin, a compound in turmeric, an Indian curry spice. A third set of rats received a standard rat diet and served as a control group.

    Turmeric may help walking ability in spinal injuries

    New York Daily News - ‎Jun 27, 2012‎
    Washington, June 27 — A diet enriched with a popular omega-3 fatty acid and curcumin, found in Indian curry spice turmeric, preserved walking ability in rats with spinal-cord injury. The findings by researchers from the University of California Los ...

    Diet supplements can repair spinal injury?

    Times of India - ‎Jun 27, 2012‎
    WASHINGTON: A diet enriched with curcumin, a component of the popular Indian spice turmeric, and omega-3 fatty acid DHA can repair tissue damage and restore walking abilities in rats with spinal-cord injury, a new study claims.

    Curry and omega-3s might help those recovering from spinal injuries: study

    GlobalPost - ‎Jun 26, 2012‎
    Researchers at UCLA found that rats with spinal cord damage recovered faster when fed a diet rich in omega-3 compound DHA and curcumin, often found in curry. Omega-3 fatty acid-rich foods such as flax seeds (above) may help to improve walking ability ...

     

  • Turmeric boosts immune system - study

    Independent Online - 17 Jun 2012
    US research has shown that curcumin, which is found in the popular curry spice turmeric, causes a sizeable increase in a protein that boosts the immune system.
  • Curry spice turmeric may help prevent Alzheimer's disease

    Food Consumer - 11 Jun 2012
    Tuesday June 2012 (foodconsumer.org) -- A new report suggests that curcumin, a dietary polyphenol found in the curry spice turmeric may be used as a ...
  • Curry Ingredient Curcumin May Increase Protein Levels In Immune ...

    South Asia Mail - 8 Jun 2012
    The cooking spice turmeric is not only a vital ingredient in many curries, it has also been used for 2500 years as a medicinal compound in the Ayurvedic system ...
  • Drs. Oz and Roizen: Five ways to keep your brain sharp

    Kansas.com - 5 Jun 2012
    To keep your brain young, get plenty of vitamin D-3, coffee and curcumin (found in ... And if you like coffee and curcumin, these help remove brain cell poop, but ...
  • Turmeric curry to boost immunity

    Hindustan Times - 29 May 2012
    Researchers in Oregon State University in the US found that curcumin, a major ... Prof Gombart said the impact of curcumin wasn't nearly as potent as that of ...
  • Curry Fires up Immune System

    Newsmax Health - 29 May 2012
    Curcumin, found in the cooking spice turmeric, boosts the immune system's ability ... New research at Oregon State University has discovered that curcumin -- a ...
  • New role identified for compound used in ancient medicine

    domain-B - 29 May 2012
    New research has discovered that curcumin, a compound found in the cooking spice turmeric, can cause a modest but measurable increase in levels of a ...
  • Curry could help keep you fighting fit: study

    New Zealand Herald - 28 May 2012
    A new study by US researchers has found curcumin - a compound in popular curry spice, ... "Curcumin is generally consumed in the diet at fairly low levels," Prof ...
  • How Curry Spice Helps The Immune System Kill Bacteria

    Huffington Post Canada - 28 May 2012
    Curcumin is a compound found in turmeric, a flavourful, orange and yellow spice that is a key ingredient in South Asian and Middle Eastern cuisine. The spice ...
  • A curry a day might just keep the doctor at bay

    JOE - 28 May 2012
    According to the Journal of Nutritional Biochemistry, curcumin helps the body to fight ... Professor Adrian Gombart of Oregon State University said: 'Curcumin is ...
  • Curcumin Termed to be Potential Enough to Fight Infectious Diseases

    French Tribune - 28 May 2012
    It has been subjected that curcumin found in turmeric, which is spice, majorly used in South Asian and Middle Eastern cuisine, can help prevent infection.
  • Curry may boost your immune system

    Minneapolis Star Tribune   - 26 May 2012
    The researchers reported in the Journal of Nutritional Biochemistry that curcumin, a compound found in the cooking spice turmeric, can cause a modest but ...
  • Yellow makes turmeric tick

    Calcutta Telegraph - 26 May 2012
    New Delhi, May 26: Curcumin, the yellow ingredient of turmeric, increases levels of an anti-microbial protein, according to a new research study that scientists ...
  • Scientists Discover As To How a Curry Ingredient Can Help Avoid ...

    French Tribune - 26 May 2012
    It has been reported that curcumin, a major component found in turmeric, which is vastly used as a main ingredient in South Asian and Middle Eastern cuisine, ...
  • New insight into how curcumin supports the immune defense system ...

    ProHealth - 25 May 2012
    Curcumin tripled production of the CAMP peptide – the only one of its kind known in humans, and able to kill a broad range of pathogens.
  • Scientists Discover How Curry Spice Strengthens Immune ...

    Medical Daily - 25 May 2012
    Eating curry may help prevent new infections by strengthening the immune system, scientists say.
  • Delicious news: Curry might help keep you healthy

    OregonLive.com - 25 May 2012
    Researchers at OSU's Linus Pauling Institute discovered that curcumin, found in turmeric, can boost levels of cathelicidin antimicrobial peptide, a protein known ...
  • New Study Shows Some Curry Dishes Boost Immune System

    Sci-News.com - 25 May 2012
    Curcumin, a principal curcuminoid found in the popular Indian spice turmeric ... published in the Journal of Nutritional Biochemistry, suggests that curcumin, ...
  • Foods that fight cancer

    Food Consumer - 23 May 2012
    Curcumin is a major ingredient of the spice turmeric. Many studies have indicated curcumin helps prevent cancer. A number of mushrooms known as "medicinal ...
  • Natural remedies for pain relief

    SheKnows.com - 22 May 2012
    A simple, but powerful formula that includes curcumin, boswellia, DLPA, and ... Curcumin has become very popular as a supplement in the past few years.
  • Why a curry could save a life

    The Sun - 20 May 2012
    Curcumin, the yellow super-nutrient in turmeric, has health-promoting effects ... designed to see whether curcumin can work alongside chemotherapy drugs, ...
  • Benefits of Turmeric Detailed by Natural Health Sherpa

    SBWire (press release) - 18 May 2012
    Curcumin found in turmeric has several health benefits that Natural Health Sherpa ... In one study that compared the effectiveness of curcumin – the active ...
  • Can curry help fight cancer? Researchers launch trial to find out

    Cordis News - 8 May 2012
    They will investigate whether tablets containing curcumin, which is found ... This work will build on previous studies showing that curcumin can enhance the ...
  • Curry chemical's ability to fight cancer put to the test

    BBC - 7 May 2012
    Earlier studies have shown that curcumin can enhance the ability of ... "The prospect that curcumin might increase the sensitivity of cancer cells to ...
  • Researchers Looking to Test Curcumin for Bowel Cancer Treatment

    Technorati - 6 May 2012
    Researchers from UK have started working on the curry ingredient curcumin to find whether curcumin can help in increasing the therapeutic ability of ...
  • Curry's benefits in cancer prevention being studied

    CBC.ca - 5 May 2012
    A spice found in turmeric called curcumin has already been linked to a range of health benefits and previous studies have shown that it can beat cancer ...
  • Students with IV Infusions Stir Controversy

    CRIENGLISH.com - 4 May 2012
    Scientists will supplement standard chemotherapy with pills containing curcumin, a compound found in the yellow curry spice turmeric.
  • Curcumin Enhances Effect of Chemotherapy

    Visit Bulgaria - 3 May 2012
    Yet again, it has been revealed that curcumin, a compound found in turmeric, is effective in enhancing the effect of chemotherapy.
  • Curry's ability to fight cancer put to the test

    Myjoyonline.com - 2 May 2012
    Curcumin, which is found in the spice turmeric, has been linked to a range of ... Now a trial at hospitals in Leicester will investigating giving curcumin ...
  • Curry ingredient in cancer research

    Aberdeen Evening Express - 1 May 2012
    Scientists will supplement standard chemotherapy with pills containing curcumin, a compound found in the yellow curry spice turmeric.
  • Trial launched into curry chemical's cancer-fighting properties

    Medical Xpress - 28 Apr 2012
    Earlier studies have shown that curcumin can enhance the ability of chemotherapy to kill bowel cancer cells in the lab. The trial is being funded by Hope ...
  • Medics try cancer treatments

    This is Leicestershire - 27 Apr 2012
    Laboratory research has already shown curcumin can improve the ... "The prospect that curcumin might increase the sensitivity of cancer cells to ...
  • Curcumin Health Benefits Revealed

    TopNews United States - 26 Apr 2012
    However, now it is expected that the number would reduce, as a new study has been done, which has found curcumin to be quite effective in treating cancer.
  • Turmeric Component Tested For Its Ability to Treat Bowel Cancer ...

    TopNews New Zealand - 25 Apr 2012
    Many studies have proposed that chemical, Curcumin, which is present in turmeric, can be beneficiary for many health ailments. It has been exaggerated that ...
  • Curry --- A Promising Cancer-Fighter?

    Kozmedia News - 24 Apr 2012
    Curcumin, which is found in the spice turmeric, has been linked to a range of health benefits. Studies have already shown that it can beat cancer cells ...
  • Curry ingredient curcumin 'could help treat bowel cancer'

    Metro - 23 Apr 2012
    (Picture: PA) A joint Cancer Research UK and University of Leicester team is hoping to discover whether pills containing curcumin - a compound found in ...
  • Curcumin is the key

    Express.co.uk - 22 Apr 2012
    Now, patients with advanced bowel cancer are set to be give tablets packed with curcumin to discover whether it can boost the effect of more powerful, ...
  • Turmeric for obesity

    Nature.com - 20 Apr 2012
    Combined with two other kitchen essentials — pepper and onion — curcumin, the key compound of turmeric, has been shown to control these metabolic parameters ...
  • Turmeric could help in fight against diabetes

    Diabetes.co.uk - 18 Apr 2012
    Researchers have claimed that an active ingredient of turmeric called curcumin could help in the fight against obesity and diabetes, as well as excessive ...
  • Turmeric extract can lower obesity and diabetes risk: Study

    India Today - 17 Apr 2012
    Curcumin - an ingredient derived from turmeric or haldi - combined with extracts ... The combination which goes by acronym CPQ - curcumin, piperine (derived ...
  • Turmeric Extract May Lower Risk of Heart Attack after Bypass

    Medical Daily - 16 Apr 2012
    Half of the patients were given pills containing curcumin and the other half was given curcumin-free placebo pills. The pills were given three days before ...
  • Turmeric lessens risk of heart attack

    Healthcare Today - 16 Apr 2012
    Of the 121 patients, all of whom had received non-emergency bypass surgery between 2009 and 2011, half were given one gram of curcumin capsules four times a ...
  • Turmeric Might Work Wonders For the Ailing Heart

    TopNews New Zealand - 16 Apr 2012
    Curcumin has for many years now been shown to reduce inflammation and to reduce oxygen toxicity or damage caused by free radicals in a number of ...
  • Turmeric lowers heart attack risk post-surgery

    Newstrack India - 16 Apr 2012
    Curcumin, the yellow pigment found in the spice contains antioxidant and anti-inflammatory qualities. Bypass surgery improves the blood flow to the heart.
  • Curcumin shows promise in easing rheumatoid arthitis pain

    Chicago Daily Herald - 16 Apr 2012
    Today their healing potential is again being rediscovered, especially curcumin. In one recent medical study, curcumin was found to be better than ...
  • Turmeric extract may protect heart after surgery

    Chicago Tribune - 13 Apr 2012
    Half of those patients were given one-gram curcumin capsules to take four times a day, starting three days before their surgery and continuing for five days ...

    Curcumin Shows Promise for Parkinson's Disease

    PsychCentral.com - 11 Apr 2012
    By Traci Pedersen Associate News Editor Curcumin, a compound found in the spice turmeric, is able to prevent the clumping of a protein associated with ...
  • Turmeric, prostate cancer study

    Deccan Herald - 7 Apr 2012
    A study conducted in Japan on curcumin, another name for turmeric, showed positive results in ... “Curcumin is used as a supplement in Japanese food.
  • Spice Up Your Life and Fight Pain With Curcumin


     
    Everyday Health - 2 Apr 2012
    And modern-day medicine has backed up these claims with research into curcumin, the active ingredient in turmeric. Here's a recent example: At Baylor ...
  • Curcumin Holds Promise as Treatment for Brain Tumors


     
    Medscape - 29 Mar 2012
    Curcumin, a major component of the spice turmeric, has been shown to have chemopreventive and chemotherapeutic properties. Past research also demonstrates ...
  • You can spice up meals with real vitamins, nutrients


     
    Wonder Woman - 28 Mar 2012
    Diners could reach for the resveratrol or curcumin the same way as they might for salt or pepper, he said. "Once the nutraceutical is enveloped, ...
  • Turmeric Found in Diabetes Support Supplements Lowers A1C Levels ...


     
    PR Web (press release) - 27 Mar 2012
    Administration of turmeric or curcumin to diabetic rats reduced the blood sugar, ... Turmeric and curcumin supplementation also reduced the oxidative stress ...
  • Curcumin shows promise in Parkinson's disease


     
    Examiner.com - 25 Mar 2012
    Although it's premature to start taking curcumin to treat Parkinson's disease, the popular culinary compound found in the spice turmeric has shown promise ...
  • Curcumin supported greater improvement in RA disease activity ...


     
    ProHealth - 24 Mar 2012
    Curcumin is a component of the curry spice, turmeric. Recently a similar study involved osteoarthritis patients.] Curcumin is known to possess potent ...
  • Curcumin induces the apoptosis of human monocytic leukemia THP-1 ...


     
    7thSpace Interactive (press release) - 24 Mar 2012
    Curcumin is a principal compound of turmeric, commonly used to treat tumors and other diseases. However, its anti-cancer activity in human acute monocytic ...
  • Parkinson's disease may be attacked by curcumin


     
    Examiner.com - 23 Mar 2012
    Nutrition Horizon has reported "Curcumin Shows Promise in Attacking Parkinson's Disease." Michigan State University (MSU) researchers have found that ...
  • Curcumin may have Parkinson's promise: Study


     
    NutraIngredients.com - 23 Mar 2012
    Intake of the tumeric spice curcumin could help to reduce clumping of proteins associated with the onset of Parkinson's disease, according to new research.
  • 15 Vegan Superfoods You Should Be Eating Right Now


     
    Ecorazzi - 23 Mar 2012
    Curcumin, which the compound that gives turmeric its distinct color, is considered ... Dr. Oz suggests getting your daily does of curcumin via turmeric tea, ...
  • 13 Foods That Fight Allergies


     
    Care2.com - 22 Mar 2012
    The main ones include: anthocyanin, curcumin, hesperetin, and quercetin in your diet. Don't worry about remembering their names.
  • Expert Says You Can Fight Pain Naturally


     
    MyFox Detroit - 22 Mar 2012
    On Thursday, he explained the medicinal secrets of Curcumin during FOX 2 News Morning. If you'd like to meet Lemerond, he'll be at the Better Health Market ...
  • Curcumin Effective in Averting Parkinson's


     
    NewsPoint Africa - 22 Mar 2012
    As per a research, which has been published in the Journal of Biological Chemistry, it has been revealed that curcumin, an active compound found in turmeric ...
  • Curcumin nudges sluggish protein folding


     
    Futurity: Research News - 21 Mar 2012
    By bumping up the speed of protein folding, curcumin—a compound in the spice turmeric—moves it out of a dangerous speed zone allowing it to avoid clumping ...
  • Curcumin 'may treat Parkinson's disease'


     
    Netdoctor - 21 Mar 2012
    Curcumin, a compound found in the spice turmeric, may be beneficial for people with Parkinson's disease, US scientists say. About 120000 people in the UK ...
  • Turmeric compound raises new hopes for treating for Parkinson's ...


     
    Newstrack India - 21 Mar 2012
    Curcumin? has been found to be very effective in prevention of the accumulation of a ... Moreover, curcumin is an active ingredient found in spice turmeric.
  • Turmeric compound shows promise for Parkinson's treatment


     
    Newstrack India - 20 Mar 2012
    Washington, March 21 (ANI): Curcumin, a compound found in the spice turmeric, has been found to be effective at preventing clumping of a protein involved in ...
  • Curcumin Can Combat Parkinson's Disease According To New Study


     
    Doctor Tipster - 20 Mar 2012
    Curcumin, a compound of an asian spice known as turmeric, can be the next cure for Parkinson disease. It was discovered by researchers at Michigan State ...
  • Smuggling medicines in food


     
    Chemistry World - 20 Mar 2012
    To address this problem, Janaswamy and his team encapsulated curcumin molecules (a plant ... Schematic encapsulation of curcumin in the hydrocolloid matrix.
  • Is Curcumin The Pain-Free Spice Of Life?


     
    CBS - 18 Mar 2012
    Terry Lemerond is a natural health expert who believes in the power of curcumin something he calls a super spice: “It's an amazing plant, ...
  • Studies Show How Vitamin D3 Helps Clear Amyloid in AD


     
    Medscape - 15 Mar 2012
    "This new study helped clarify the key mechanisms involved, which will help us better understand the usefulness of vitamin D3 and curcumin as possible ...
  • EuroPharma Adopts Turmeric in ABC's Adopt-an-Herb Program


     
    Natural Products INSIDER - 14 Mar 2012
    EuroPharma's support ensures the latest published scientific and clinical research on turmeric and its key beneficial compound, curcumin, will be available ...
  • Curcumin, but not Prima-1, decreased tumor cell proliferation in ...


     
    UroToday - 14 Mar 2012
    Among the mediators of this effect of smoking is nuclear factor-kappa B. Curcumin suppresses cellular transformation by downregulating the activity of ...
  • Study Shows How Vitamin D Fights Alzheimer's


     
    CalorieLab Calorie Counter News - 13 Mar 2012
    Previous studies demonstrated that curcumin, an ingredient isolated from the spice turmeric, induced the same activity.
  • More Insight on Possible Role of Vitamin D Against Alzheimer's


     
    Health.com - 13 Mar 2012
    Previous research by the same University of California, Los Angeles, team found that therapy with vitamin D3 and curcumin — a chemical found in the spice ...
  • Eat yourself healthy: your dose of cancer-busting foods


     
    Mail & Guardian Online - 13 Mar 2012
    The Indian spice turmeric contains curcumin, which has been used for ... Scientific research suggests that curcumin may help to prevent or treat cancer.
  • Alzheimer's: Study Shows How The Nutrient Can Help ...


     
    Huffington Post - 12  Mar 2012
    "This new study helped clarify the key mechanisms involved, which will help us better understand the usefulness of vitamin D3 and curcumin as possible ...
  • Spice May Trigger Mesothelioma Cell Breakdown


     
    Surviving Mesothelioma - 11 Mar 2012
    A team of researchers at Keio University in Tokyo report that curcumin, the primary component in ... “Curcumin, which has a long history as a dietary spice, ...
  • Curcumin May Reduce Free Light Chains In Patients With MGUS And ...


     
    The Myeloma Beacon - 10 Mar 2012
    The Australian researchers also found that patients had reduced levels of bone breakdown while taking curcumin. “A number of the patients in this study did ...
  • Vitamin may help combat Alzheimer's Disease


     
    Examiner.com - 8 Mar 2012
    Curcumin is a chemical found in turmeric spice. Scientists believed that curcumin, like Vitamin D3, stimulated the immune system to clear amyloid beta.
  • Inflammatory Bowel Disease: Alternatives Plus Conventional Drugs ...


     
    EmpowHer - 7 Mar 2012
    Curcumin, found naturally in turmeric spice, has also been reported to have significant anti-inflammatory properties. Dr. Rebecca A. Taylor and Dr. Mandy C.
  • Alzheimer's plaques


     
    eMaxHealth - 6 Mar 2012
    "This new study helped clarify the key mechanisms involved, which will help us better understand the usefulness of vitamin D3 and curcumin as possible ...
  • Dr. Oz: Health perks you can get from spices


     
    Sarasota Herald-Tribune - 5 Mar 2012
    Dr. Mike carries a mustard pack in his pocket to get a daily dose of curcumin, the power drive in turmeric (it's what makes mustard yellow) that protects ...
  • Acupuncture & Chinese Medicine Protect Liver – New Research


     
    HealthCMI - 3 Mar 2012
    New research demonstrates that acupuncture combined with oral curcumin intake ... Researchers examined the efficacy of curcumin and acupuncture both ...
  • Find the spice of life


     
    The Idaho Statesman - 2 Mar 2012
    Dr. Mike carries a mustard pack in his pocket to get a daily dose of curcumin, the power drive in turmeric (it's what makes mustard yellow) that protects ...
     

    The anti-inflammatory role of curcumin in obesity and obesity-related metabolic diseases
    Eur J Nutr. 2011 Apr;50(3):151-61. Epub 2011
    School of Life Sciences, College of Natural Sciences
    Researchers reviewed the last ten years of curcumin science as it applies to supporting weight loss and preventing obesity-related disease. Their conclusion is, “The modulation of several cellular transduction pathways by curcumin has recently been extended to elucidate the molecular basis for obesity and obesity-related metabolic diseases. These findings might enable novel phytochemical treatment strategies as well as curcumin translation to the clinical practice for the treatment and prevention of obesity-related chronic diseases. Furthermore, the relatively low cost, safety and proven efficacy of curcumin make it advisable to include curcumin as part of healthy diet.”

    Targeting Inflammation-Induced Obesity and Metabolic Diseases by Curcumin and Other Nutraceuticals
    Cytokine Research Laboratory, Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030
    Extensive research within the past two decades has revealed that obesity, a major risk factor for type 2 diabetes, atherosclerosis, cancer, and other chronic diseases, is a proinflammatory disease. Several spices have been shown to exhibit activity against obesity through antioxidant and anti-inflammatory mechanisms. Among them, curcumin, a yellow pigment derived from the spice turmeric (an essential component of curry powder), has been investigated most extensively as a treatment for obesity and obesity-related metabolic diseases. Curcumin directly interacts with adipocytes, pancreatic cells, hepatic stellate cells, macrophages, and muscle cells. There, it suppresses the proinflammatory transcription factors nuclear factor-kappa B, signal transducer and activators of transcription-3, and Wnt/β-catenin, and it activates peroxisome proliferator-activated receptor-γ and Nrf2 cell-signaling pathways, thus leading to the downregulation of adipokines, including tumor necrosis factor, interleukin-6, resistin, leptin, and monocyte chemotactic protein-1, and the upregulation of adiponectin and other gene products. These curcumin-induced alterations reverse insulin resistance, hyperglycemia, hyperlipidemia, and other symptoms linked to obesity.
     

  • Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern target- Bokyung Sung 
    Cytokine Research Laboratory, Department of Experimental Therapeutics, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA
    Curcumin (diferuloylmethane), a yellow pigment in the spice turmeric (also called curry powder), has been used for centuries as a treatment for inflammatory diseases. Extensive research within the past two decades has shown that curcumin mediates its anti-inflammatory effects through the downregulation of inflammatory transcription factors (such as nuclear factor κB), enzymes (such as cyclooxygenase 2 and 5 lipoxygenase) and cytokines (such as tumor necrosis factor, interleukin 1 and interleukin 6). Because of the crucial role of inflammation in most chronic diseases, the potential of curcumin has been examined in neoplastic, neurological, cardiovascular, pulmonary and metabolic diseases. The pharmacodynamics and pharmacokinetics of curcumin have been examined in animals and in humans. Various pharmacological aspects of curcumin in vitro and in vivo are discussed in detail.Trends Pharmacol Sci. 2009 Feb;30(2):85-94. Epub 2008 Dec 26
    Spice Rack...Or Medicine Chest?
    Nutrition Action Health Letter
    "Curcumin protects the brain cells in every animal model of traumatic brain injury, whether it's stroke, Alzheimer's disease, Huntington's disease, or mad cow disease," says Gregory Cole, associate director of the Alzheimer's Disease Center at the University of California, Los Angeles. "What's unique about Curcumin," Cole notes, "is that it binds directly to beta-amyloid deposits in the brain and reduces their size." Beta-amyloid is a protein fragment that builds up between brain cells of people with Alzheimer's disease....
    Science Daily Magazine
    How Plants Protect Us From Disease
    "Everyday foods, beverages, and spices contain healthful compounds that help us fight harmful inflammation. And, in doing that, these phytochemicals may also reduce our risk of diseases associated with chronic inflammation, including cancer and diabetes."
    Curcumin Curry Power
    Science News Magazine
    "The list of Curcumin's effects goes on and on, and they're all in your favor...in addition to its anti-inflammatory and antioxidant properties, Curcumin has several effects that may work in tandem to protect the brain from plaques in other ways. "If Curcumin had a single molecular target, it probably would not be as good a drug," M.D. Anderson Cancer Center in Houston. "But because it has multiple targets, it's very attractive."

    Health: The Fires Within
    Time Magazine
    Chronic inflammation may be the engine that drives many of the most feared illnesses of middle and old age. This concept is so intriguing because it suggests a new and possibly much simpler way of warding off disease. Instead of different treatments for, say, heart disease, Alzheimer's and colon cancer, there might be a single, inflammation-reducing remedy that would prevent all three.

    The 'inflammation theory': Immune-system errors linked to more illnesses
    The Seattle Times
    "Medical researchers are becoming increasingly convinced that the most primitive part of the immune system (inflammation), may play a crucial role in some of the most devastating afflictions of modern humans, including heart disease, cancer, diabetes and possibly Alzheimer's."
    Did evolution give us inflammatory disease?
    American Journal of Human Genetics
    Researchers demonstrate that some variants in our genes that could put a person at risk for inflammatory diseases such as multiple sclerosis, Crohn's disease or rheumatoid arthritis, have been the target of natural selection over the course of human history. The findings suggest that in the past these variants rose in frequency in the human population to help protect us against viruses, bacteria and other pathogens. But now in our modern world, the environment and exposure to pathogens has changed, and the genetic variants that were originally meant to protect us, now make an autoimmune reaction more likely.
    Curcumin at M.D. Anderson Cancer Center
    The University of Texas, MD Anderson Cancer Center
    Curcumin has been shown to prevent a large of number of cancers in animal studies. Laboratory data indicate that Curcumin can inhibit tumor initiation, promotion, invasion, angiogenesis and metastasis. Epidemiological evidence indicate that incidence of certain cancers is less in people who consume Curcumin than in those who do not. Recent evidence indicates that, besides chemopreventive activity, Curcumin may also be effective in the treatment of cancer. Curcumin is currently under investigtion for its anti-cancer and anti-inflammatory effects at M. D. Anderson Cancer Center and other medical institutions.
    Curcumin Spice Healer
    Scientific American Magazine
    An ingredient in curry shows promise for treating Alzheimer's, cancer and other diseases.
    "A chapter in a forthcoming book, for instance, describes the biologically active components of Turmeric--Curcumin and related compounds called Curcuminoids--as having antioxidant, anti-inflammatory, antiviral, antibacterial and antifungal properties, with potential activity against cancer, diabetes, arthritis, Alzheimer's disease and other chronic maladies. And in 2005 nearly 300 scientific and technical papers referenced Curcumin in the National Library of Medicine's PubMed database, compared with about 100 just five years earlier. Scientists who sometimes jokingly label themselves Curcuminologists are drawn to the compound both because of its many possible valuable effects in the body and its apparent low toxicity. They ponder how the spice or its derivatives might be used, not just as a treatment but as a low-cost preventive medication for some of the most feared ailments. As a treatment, it also has some enticing attributes. Because Curcumin targets so many biological pathways, it could have benefits for cancer therapy: malignant cells may be slow to acquire resistance to it and so might have to go through multiple mutations to avoid the substance's multipronged attack." 1 2 3 4
  • Previous news and studies on Curcumin and Turmeric.
    turmeric-curcumin.com/curcumin.html
     

    Medical research studies and university clinical trials on Curcumin and Turmeric.

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    National Library of Medicine Gold Bamboo

    Medscape

    GreenMedInfo Worlds Healthiest Foods
    Science News Daily
     

    Scientific journals with published studies of Curcumin and Turmeric.

    American Journal of Physiology - 277: 320-29
    Age - 18:167-9
    Agents and Actions - 28:298-303
    Alimentary Pharmacology and Therapeutics - 13(2):245-249
    Alternative Medicine Review - 4(3):178-88, 6(2):167-187, 7(5):404-9
    American Journal of Clinical Nutrition - 64(5):761-766
    American Journal of Physiology: Gastrointestinal and Liver Physiology 284(1):85-95, 284(2):321-7
    American Surgeon - 64(1):47-51
    Annals of the New York Academy of Sciences - 973:250-4
    Anticancer Drugs - 8(5):470-81
    Anti Cancer Research - 11: 593-596,  19(5A):3675-80, 20(3a):1733-8,

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    What is Turmeric-Curcumin.com?

    Turmeric-Curcumin.com is the name of our company and website, founded by researchers who believe the best prescription is knowledge. Since the year 2000, our company philosophy has been to offer the certified highest quality Curcumin 95% extract, the best customer service, the lowest prices in the industry, and none of the marketing hype. Unlike other suppliers, we do not sell 500 products, or even 5 products. We remain dedicated and focused on the most powerful, healthful and important compound in botanical medicine; Curcumin, concentrated and standardized to 95% purified extract. This extraordinary spice extract has generated such interest that universities and medical centers around the world are continually conducting research studies and discovering new benefits, with multiple ongoing human clinical trials. Due to it's potent antioxidant power, Curcumin has been recognized as one of the most promising food-derived compounds in fighting a variety of degenerative diseases. The scientific evidence remains overwhelming, demonstrating the many health benefits via in vitro, in vivo and human clinical studies. You will receive 100% additive free products; no sugars or other sweeteners, no artificial colors or flavors, no starch, no sodium, no soy, no yeast, no wheat, no gluten, no dairy, no preservatives, no black pepper extract or "bioperine" (actually a trademark of Piper nigrum by the Sabinsa corporation), no GMO, no dyes, no gums or any other unnecessary compounds. You may contact support@turmeric-curcumin.com or call with any questions or comments and we will respond as quickly as possible.

     

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